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Association of IL-18 promoter polymorphism with liver disease severity in HCV-infected patients

✍ Scribed by K. Manohar; P. V. Suneetha; Sukriti; Nirupama Trehan Pati; Abhishek C. Gupta; Syed Hissar; Puja Sakhuja; S. K. Sarin


Book ID
107593823
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
268 KB
Volume
3
Category
Article
ISSN
1936-0533

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The pathogenesis of chronic hepatitis C virus (HCV) infection remains unclear. Tumour necrosis factor alpha (TNF-alpha) is alleged to contribute in the pathogenesis of chronic HCV infection. Single nucleotide polymorphism in TNF-alpha and -beta genes could influence the outcome of HCV infection. The