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Association of HLA–DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a followup study

✍ Scribed by Derkjen Van Zeben; Johanna M. W. Hazes; Aeilko H. Zwinderman; Arnold Cats; Geziena M. T. Schreuder; Joe D'Amaro; Ferdinand C. Breedveld

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 772 KB
Volume: 34
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780340707

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## Abstract ## Objective To determine whether the HLA–DRB1 shared epitope (SE) is associated with early mortality and specific causes of death in rheumatoid arthritis (RA). ## Methods HLA–DRB1 genotyping was carried out on blood samples from 767 patients recruited for the Early RA Study (ERAS),