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Association of HLA-DRB1*1501 tagging rs3135388 gene polymorphism with multiple sclerosis

✍ Scribed by Benešová, Yvonne; Vašků, Anna; Štourač, Pavel; Hladíková, Magdalena; Fiala, Adam; Bednařík, Josef

Book ID: 122966074
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 179 KB
Volume: 255
Category: Article
ISSN: 0165-5728
DOI: 10.1016/j.jneuroim.2012.10.014

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## Abstract Susceptibility to multiple sclerosis (MS) is associated genetically with human leucocyte antigen (HLA) class II alleles, including DRB1\*1501, DRB5\*0101, and DQB1\*0602, and it is possible that these alleles contribute to MS through an enhanced ability to present encephalitogenic myeli