Association of HLA class II allele and haplotype frequencies with chronic myelogenous leukemia and age-at-onset of the disease

Class I associations and frequencies of

Class I associations and frequencies of class II HLA-DRB alleles by RFLP analysis in children with rheumatoid-factor-negative juvenile chronic arthritis

✍ H. I. Brunner; E. Ivaskova; J. P. Haas; A. Andreas; E. Keller; J. Hoza; S. Havel 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 541 KB

A total of 94 patients with juvenile chronic arthritis (JCA) was tested for HLA class I by serology and for class II by RFLP typing. Early onset JCA (EOPA) is associated with HLA-A2, DR5 and DR8 in both males and females. The combination (joint occurrence) of these JCA associated alleles (A2, DR5, D