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Association of genetic polymorphisms in the RET-protooncogene and NRG1 with Hirschsprung disease in Thai patients

✍ Scribed by Phusantisampan, Theerawut; Sangkhathat, Surasak; Phongdara, Amornrat; Chiengkriwate, Piyawan; Patrapinyokul, Sakda; Mahasirimongkol, Surakameth


Book ID
120035018
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
456 KB
Volume
57
Category
Article
ISSN
1435-232X

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Novel intronic polymorphisms in the RET
✍ Guido Fitze; Mandy Schierz; Eberhard Kuhlisch; Matthias Schreiber; Andreas Ziegl πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 46 KB

Germline mutations of the RET proto-oncogene have been found in familial and sporadic forms of Hirschsprung disease (HSCR), but also in the autosomal dominantly inherited multiple endocrine neoplasia type 2 (MEN2) syndromes, which comprise the medullary thyroid carcinoma (MTC) as an obligatory featu