Association of Epstein–Barr virus antibody levels with precancerous gastric lesions in a high-risk cohort
✍ Scribed by Aaron J. Schetter; Wei-cheng You; Evelyne T. Lennette; Mitchell T. Gail; Charles S. Rabkin
- Book ID
- 108584063
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 76 KB
- Volume
- 99
- Category
- Article
- ISSN
- 1347-9032
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## Abstract Promoter hypermethylation of various tumor‐related genes is extremely frequent in gastric carcinoma (GC) associated with Epstein‐Barr virus (EBV). To investigate the significance of the promoter methylation in this type of GC, we examined the methylation densities of the promoter region
## Abstract ## BACKGROUND Serologic measurement of antibodies to Epstein–Barr virus (EBV) immunoglobulin A/viral capsid antigen (IgA/VCA) and early antigen (IgA/EA) has been used widely to screen for nasopharyngeal carcinoma (NPC) in China. Recently, it was found that plasma EBV DNA concentration
Epstein-Barr virus (EBV) has been associated with the most common form of stomach neoplasms, the gastric carcinoma (GC). The presence of EBV-encoded small RNAtype-1 (EBER-1), a marker for EBV infection was analyzed by in situ hybridization (ISH) in 185 formalin-fixed and paraffinembedded cases of GC