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Association of DNMT1 and DNMT3B polymorphisms with breast cancer risk in Han Chinese women from South China

✍ Scribed by Sun, M.-Y.; Yang, X.-X.; Xu, W.-W.; Yao, G.-Y.; Pan, H.-Z.; Li, M.


Book ID
120232952
Publisher
Ribeiro Preto foundation for Scientific Research (FUNPEC)
Year
2012
Tongue
English
Weight
495 KB
Volume
11
Category
Article
ISSN
1676-5680

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## Abstract p21^Cip1^ and p27^Kip1^ are cyclin‐dependent kinase inhibitors, which can arrest cell proliferation and serve as tumor suppressors. Reduced protein expression of p21^Cip1^ and p27^Kip1^ was frequently observed in a subset of cancers, including breast cancer. In this study, we hypothesiz