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Association of core promoter mutations with viral breakthrough in chronic hepatitis B patients on long-term lamivudine therapy

โœ Scribed by Syed Naqui Kazim; Ranjit Chauhan; Bhudev Chandra Das; Shiv Kumar Sarin

Book ID
108950990
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
347 KB
Volume
21
Category
Article
ISSN
0815-9319

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## Abstract HBe antigen (HBeAg) loss or seroconversion can occur during lamivudine therapy. The purpose of this study was to analyze nucleotide sequences in precore and core promoter regions, and examine the influence of mutations in these regions on the disappearance of HBeAg during lamivudine the