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Association of centromeric heterochromatin with the nucleolus in mouse sertoli cells

✍ Scribed by Jean, Pierre ;Hartung, Mich�le ;Mirre, Christian ;Stahl, Andr�

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 519 KB
Volume: 205
Category: Article
ISSN: 0003-276X
DOI: 10.1002/ar.1092050402

No coin nor oath required. For personal study only.

✦ Synopsis

In adult Sertoli cells of most strains of mice, all the centromeric heterochromatin is condensed in two chromocenters, one on each side of a single, large nucleolus. In a random-bred Swiss OF-1 strain, however, the nucleus has a different structural organization. Part of the heterochromatin is seen as chromocenters in contact with the nucleolus; the rest of it is dispersed in granules of unequal size in the nucleoplasm. Such an unusual spatial arrangement of heterochromatin in interphase nucleus cannot be explained either by a difference in the nucleolar organizing regions or by a polymorphism of the C-banding of metaphase chromosomes.

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