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Association of BDNF Met66Met polymorphism with arm tremor in cervical dystonia

✍ Scribed by Justus L. Groen; Katja Ritz; Daan C. Velseboer; Majid Aramideh; Jacobus J. van Hilten; Agnita J.W. Boon; Bart P. van de Warrenburg; Frank Baas; Marina A.J. Tijssen


Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
712 KB
Volume
27
Category
Article
ISSN
0885-3185

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Background Brain-derived neurotrophic factor (BDNF) plays an important role in the regulation of synaptic plasticity and neurotransmitter release across multiple neurotransmitter systems. Recent studies have suggested that BDNF plays a role in the pathogenesis of psychiatric symptoms in patients wit

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## Abstract The classification of arm tremor in cervical dystonia is a controversial issue. There have been many, at times passionate disputes in the movement disorder community about whether it should be classified as a manifestation of dystonia or essential tremor associated with dystonia. There

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## Abstract The Met66 allele of the Val66Met polymorphism in the brain‐derived neurotrophic factor (BDNF) gene has been reported to be associated with anorexia nervosa (AN), and also lower minimum body mass index (BMI) and higher harm avoidance in AN. We genotyped the Val66Met polymorphism (rs6265)