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Association of antipsychotic induced weight gain and body mass index with GNB3 gene: A meta-analysis

✍ Scribed by Renan P. Souza; Vincenzo De Luca; Giovanni Muscettola; Daniela V.F. Rosa; Andrea de Bartolomeis; Marco Romano Silva; James L. Kennedy


Book ID
116841405
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
597 KB
Volume
32
Category
Article
ISSN
0278-5846

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## Abstract ## Objective Atypical antipsychotic drugs, in particular clozapine and olanzapine, influence cellular lipogenesis and are associated with metabolic side effects including weight gain. Insulin induced gene 2 (INSIG2) mediates feedback control of lipid synthesis and polymorphisms in the