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Association of ankylosing spondylitis with HLA-B27 and ERAP1: Pathogenic role of antigenic peptide

✍ Scribed by Chen, Bin; Li, Dahe; Xu, Weidong


Book ID
119324953
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
423 KB
Volume
80
Category
Article
ISSN
0306-9877

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Two HLA-B27 subtypes, B'2702 and B'2705, both associated with ankylosing spondylitis, were tested for binding affinity with a panel of polyalanine model nonapeptides carrying Arg at position 2 (P2) and a series of different amino acids at position 9 (P9)\_ The alpha chains were isolated from BTB(B\*