## Monoamine oxidase B (MAO -B ) is an enzyme that has relevance for Parkinson disease (PD) because of its roles in catabolizing dopamine and potentially activating exogenous neurotoxicants. A polymorphism of the gene encoding MAO-B has been identified as a single base change (A or G) in intron
Association of a new intronic polymorphism of the SOD2 gene (G1677T) with cancer
β Scribed by Daniel Hernandez-Saavedra; Joe M. McCord
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 173 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1560
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A new Msp I polymorphism (g1741G>A) in intron 3 of the human Ξ΄-aminolevulinate dehydratase
## Abstract Endothelialβderived nitric oxide, which is produced by endothelial nitric oxide synthase (eNOS), may play an important role in colorectal carcinogenesis. However, the putative contribution of common __eNOS__ genetic polymorphisms to colorectal cancer risk remains unknown. We genotyped 3
The retinoblastoma gene (RB) encodes a tumor suppressor that is inactivated in a number of different types of cancer. We searched for gross alterations of this gene in tumors of the central nervous system by using Southern blot hybridization. A common alteration was found in several tumors and was m
## Abstract Lung cancer is the leading cause of cancer mortality in the world. Although exposure to carcinogens is considered to be the main cause, genetic variation may contribute to lung cancer risk. Murine double minute 2, MDM2, is a key regulator of p53 activity and recently a polymorphism in t
## Abstract __CCND1__ mRNA is alternatively spliced to produce 2 transcripts, and the splicing pattern may be modulated by a frequent __A__870__G__ singleβnucleotide polymorphism within the conserved splice donor site of exon 4. Several studies have suggested a significant association between the _