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Association of a lymphocyte purine enzyme deficiency (5′-nucleotidase) with combined immunodeficiency

✍ Scribed by Amos Cohen; Albert Mansour; Hans-Michael Dosch; Erwin W. Gelfand


Book ID
118373682
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
387 KB
Volume
15
Category
Article
ISSN
1090-2341

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## Abstract Cultured skin fibroblasts from a patient with T‐cell immune deficiency and an absence of purine nucleoside phosphorylase activity in red cells were assayed for their capacity to metabolize inosine and guanosine. The cultured fibroblasts were lacking activity of nucleoside phosphorylase