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Association of 8p23 deletions with poor survival in head and neck cancer

✍ Scribed by Ulrike Bockmühl; Chandramohan S. Ishwad; Robert E. Ferrell; Susanne M. Gollin

Book ID
117843555
Publisher
SAGE Publications
Year
2001
Tongue
English
Weight
94 KB
Volume
124
Category
Article
ISSN
0194-5998

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## Background: Deletion of 9p21 is a common event in many human tumors, including head and neck squamous cell carcinoma (hnscc). the gene cdkn2, which encodes the protein p16, a cyclin-dependent kinase-4 inhibitor, maps to 9p21. the role of cdkn2 as the tumor suppressor gene in these neoplasms is u