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Association betweenHelicobacter pyloriseropositivity and NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism observed in outpatients and health checkup examinees

✍ Scribed by Yasuyuki Goto; Nobuyuki Hamajima; Hiroyuki Honda; Keitaro Matsuo; Kazuhito Yamamoto; Akiko Tamakoshi; Takafumi Ando; Hidemi Goto

Publisher: Springer
Year: 2005
Tongue: English
Weight: 176 KB
Volume: 8
Category: Article
ISSN: 1436-3291
DOI: 10.1007/s10120-004-0308-1

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## Abstract NQO1 is an antioxidant enzyme, important in the detoxification of environmental carcinogens. A single nucleotide polymorphism (C→T) at position 609 of the __NQO1__ cDNA has been associated with susceptibility to tumours induced by chemical carcinogens. In our case‐control study, we dete