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Association Between the M268T Polymorphism in the Angiotensinogen Gene and Essential Hypertension in a South Indian Population

โœ Scribed by M. Gopi Chand; J. Srinath; R. S. Rao; Bhaskar V. K. S. Lakkakula; Satish Kumar; V. R. Rao


Publisher
Springer
Year
2011
Tongue
English
Weight
171 KB
Volume
49
Category
Article
ISSN
0006-2928

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## Background: The substitution of tryptophan for glycine at amino acid 460 (gly460trp polymorphism) of the alpha-subunit of the heterodimeric cytoskeleton protein adducin increases renal sodium reabsorption and may be involved in the pathophysiology of essential hypertension. in the present study,