## Abstract The contribution of mossy fiber sprouting to the generation of spontaneous seizures in the epileptic brain is under dispute. The present study addressed this question by examining whether sprouting of mossy fibers is present at the time of appearance of the first spontaneous seizures in
✦ LIBER ✦
Association Between the Density of Mossy Fiber Sprouting and Seizure Frequency in Experimental and Human Temporal Lobe Epilepsy
✍ Scribed by Asla Pitkänen; Jari Nissinen; Katarzyna Lukasiuk; Leena Jutila; Leo Paljärvi; Tuuli Salmenperä; Kari Karkola; Matti Vapalahti; Aarne Ylinen
- Book ID
- 109108290
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2000
- Tongue
- English
- Weight
- 886 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0013-9580
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Genetic linkage studies in rodents and humans have identified specific chromosomal regions harboring seizure susceptibility genes. We have identified a novel polymorphism in the human alpha 2 subunit gene (ATP1A2) of the sodium potassium transporting ATPase (NaK-pump), a candidate gene for human tem