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Association between suicide attempt and a tri-allelic functional polymorphism in serotonin transporter gene promoter in Chinese patients with schizophrenia

✍ Scribed by Chi-Fa Hung; For-Wey Lung; Chien-Hsiun Chen; Elizabeth O’Nions; Tai-Hsin Hung; Mian-Yoon Chong; Ching-Kuan Wu; Jung-Kwang Wen; Pao-Yen Lin


Book ID
116773629
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
207 KB
Volume
504
Category
Article
ISSN
0304-3940

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It has been suggested that the serotonin transporter (5-hydroxytryptamine-transporter or 5-HTT) may be involved in the pathogenesis of affective disorders. Recently, Collier et al. (1996) found that the frequency of the low-activity short variant (s) of the 5-HTT-linked polymorphic region (5-HTTLPR)