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Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample

✍ Scribed by Moffatt, Miriam F; Schou, Carsten; Faux, Jennifer A; Abecasis, Gonçalo R; James, Alan; Musk, A William; Cookson, William OCM


Book ID
110025125
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
98 KB
Volume
9
Category
Article
ISSN
1018-4813

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Asthma is a common, complex human disease. Elevated serum immunoglobulin E (IgE) levels, elevated blood eosinophil counts, and increased airway responsiveness are physiological traits that are characteristic of asthma. Few studies have investigated major gene effects for these traits in a population