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Association between prevalence of pyrimethamine resistance and double mutation in pfdhfr gene in West Bengal, India

โœ Scribed by Sabyasachi Das; Subhankari Prasad Chakraborty; Satyajit Tripathy; Amiya Kumar Hati; Somenath Roy


Book ID
119650541
Publisher
Asian Pacific Journal of Tropical Medicine Press
Year
2012
Tongue
English
Weight
298 KB
Volume
2
Category
Article
ISSN
2222-1808

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Mutations in the Plasmodium falciparum pfcrt gene on chromosome 7 and possibly mutations in pfmdr1 on chromosome 5 have a role in conferring resistance against chloroquine (CQ), as do mutations of pfdhfr on chromosome 4 and pfdhps on chromosome 8 in terms of resistance against sulfadoxine/pyrimetham