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Association between polymorphisms in the XRCC1 and GST genes, and CpG island methylation status in colonic mucosa in ulcerative colitis

✍ Scribed by Tomomitsu Tahara; Tomoyuki Shibata; Masakatsu Nakamura; Masaaki Okubo; Hiromi Yamashita; Daisuke Yoshioka; Joh Yonemura; Ichiro Hirata; Tomiyasu Arisawa

Publisher
Springer
Year
2011
Tongue
English
Weight
199 KB
Volume
458
Category
Article
ISSN
1432-2307

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✍ Tomomitsu Tahara; Tomoyuki Shibata; Masakatsu Nakamura; Hiromi Yamashita; Daisuk 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 276 KB

## Abstract CpG island hyper methylation (CIHM) is one of the major events in gastric carcinogenesis. To evaluate the influence of host genetic factors in CIHM related carcinogenesis, we investigated the association between common polymorphisms in IL‐1β and TNF‐α genes, with CIHM status in the nonn