Association between oxidized LDL, obesity and type 2 diabetes in a population-based cohort, the Health, Aging and Body Composition Study

Putative association between a new polym

Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations

✍ Inka Lindner; Ulf Helwig; Diana Rubin; Yun Li; Eva Fisher; Heiner Boeing; Matthi 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 77 KB

The protein encoded by the pancreatic colipase (CLPS) gene is an essential cofactor needed by pancreatic triglyceride lipase (PNLIP) for efficient dietary lipid hydrolysis. Since the inhibition of lipase activity was shown to reduce the incidence of type 2 diabetes mellitus, we tested the hypothesis