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Association between MTHFR A1298C polymorphism and neural tube defect susceptibility: a metaanalysis

โœ Scribed by Xi W. Wang; Ya L. Luo; Wei Wang; Yu Zhang; Qing Chen; Yu L. Cheng


Book ID
113439053
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
322 KB
Volume
206
Category
Article
ISSN
1097-6868

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## Abstract ## BACKGROUND: Methylenetetrahydrofolate reductase (__MTHFR__) of the folate metabolism pathway is a candidate gene for neural tube defects (NTDs). Frequency of the second common polymorphism, A1298C, in the __MTHFR__ gene is not well known in Mexico. Conflicting results exist regardin