BACKGROUND: Polymorphisms in genes that are involved in folic acid metabolism may be important maternal risk factors for the birth of a child with nonsyndromic cleft lip and/or palate (NSCL/P). The aim of this study was to determine the involvement of polymorphic variants in four genes (MTHFR, MTHFD
✦ LIBER ✦
Association Between Maternal Smoking, Gender, And Cleft Lip And Palate in a Brazilian Population
✍ Scribed by MARTELLI, DANIELLA REIS BARBOSA; RODRIGUES, LAÍSE ANGÉLICA; PARANAÍBA, LÍVIA MARIS; DE AQUINO, SIBELE NASCIMENTO; SWERTS, MÁRIO SÉRGIO OLIVEIRA; BARROS, LETÍZIA MONTEIRO; JÚNIOR, HERCÍLIO MARTELLI
- Book ID
- 122219484
- Publisher
- Elsevier
- Year
- 2014
- Tongue
- English
- Weight
- 84 KB
- Volume
- 117
- Category
- Article
- ISSN
- 2212-4403
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## Abstract ## Objectives/Hypothesis: Interferon regulatory factor 6 (__IRF6__), the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because a number of studies have supported an association between NSCLP and single
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