Association between macroorchidism and intelligence in FMR1 premutation carriers
โ Scribed by Lozano, Reymundo; Summers, Scott; Lozano, Cristina; Mu, Yi; Hessl, David; Nguyen, Danh; Tassone, Flora; Hagerman, Randi
- Book ID
- 124073152
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 103 KB
- Volume
- 164
- Category
- Article
- ISSN
- 1552-4825
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## Abstract Premutation alleles of the fragile X mental retardation 1 (__FMR1__) gene give rise to a lateโonset movement disorder, fragile Xโassociated tremor/ataxia syndrome (FXTAS), characterized by progressive intention tremor and gait ataxia, with associated dementia and global brain atrophy. T
## Abstract While an established protocol exists for diagnosing individuals with the fragile Xโassociated tremor/ataxia syndrome (FXTAS), a quantitative measure of tremor and ataxia is needed. Using the CATSYS system to quantify movement abnormalities, we were able to record tremor, postural sway,