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Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

✍ Scribed by Jochen Hampe; Andrew Cuthbert; Peter JP Croucher; Muddassar M Mirza; Silvia Mascheretti; Sheila Fisher; Henning Frenzel; Kathy King; Anja Hasselmeyer; Andrew JS MacPherson; Stephen Bridger; Sander van Deventer; Alastair Forbes; Susanna Nikolaus; John E Lennard-Jones; Ulrich R Foelsch; Michael Krawczak; Cathryn Lewis; Stefan Schreiber; Christopher G Mathew

Book ID
117277385
Publisher
The Lancet
Year
2001
Tongue
English
Weight
79 KB
Volume
357
Category
Article
ISSN
0140-6736

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## Abstract Epidemiological observations suggest that cancer arises from chronically inflamed tissues. Inflammatory bowel disease (IBD) is a typical example since patients with longstanding IBD are at increased risk for development of colorectal cancer (CRC). Therefore, genetic factors predisposing