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Association between hTERT activation by HPV E6 proteins and oncogenic risk

✍ Scribed by Van Doorslaer, Koenraad; Burk, Robert D.


Book ID
118504230
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
174 KB
Volume
433
Category
Article
ISSN
0042-6822

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## Abstract The E6 oncoprotein from high‐risk HPV types activates human telomerase reverse transcriptase (hTERT) transcription in human keratinocytes. Studies on how E6 regulates hTERT have implicated E‐box or X‐box elements in the hTERT promoter (Veldman __et al.__, Proc Natl Acad Sci USA 2003;100