𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Association between Helicobacter pylori infection and laryngohypopharyngeal carcinoma: A case–control study and review of the literature

✍ Scribed by Jalal Rezaii; Hassan Tavakoli; Khalil Esfandiari; Hossein Ashegh; Mehrdad Hasibi; Gholamreza Ghanei; Mahnaz Khosh-Batn; Armin Rashidi

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
81 KB
Volume
30
Category
Article
ISSN
1043-3074

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background.

Gastroesophageal reflux, by exposing the pharynx to Helicobacter pylori (H. pylori), is a potential risk factor for laryngohypopharyngeal carcinoma. Its possible association has been inconsistent. In this case–control study, we investigated the relationship between H. pylori seropositivity and laryngohypopharyngeal carcinoma in Iran.

Methods.

We had 105 healthy controls (group A), 70 cases of laryngeal carcinoma (group B), and 28 cases of hypopharyngeal carcinoma group (group C). Age, sex, smoking habit, alcohol use, and H. pylori serology were determined for all subjects.

Results.

Groups were matched in age and alcohol use. Smoking and H. pylori seropositivity were more common in groups B and C, and male sex was more common in group B (compared with group A). In multivariate regression, the effect of smoking (p <.01, odds ratio [OR] = 2.92) and H. pylori seropositivity (p <.01, OR = 11.49) remained highly significant.

Conclusion.

H. pylori is an independent risk factor for laryngohypopharyngeal carcinoma. © 2008 Wiley Periodicals, Inc. Head Neck, 2008

📜 SIMILAR VOLUMES

Association between Helicobacter pylori
Association between Helicobacter pylori infection and inflammatory bowel disease: A meta-analysis and systematic review of the literature
✍ Jay Luther; Maneesh Dave; Peter D.R. Higgins; John Y. Kao 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB 👁 2 views

Background: Epidemiologic data suggest a protective effect of Helicobacter pylori infection against the development of autoimmune disease. Laboratory data illustrate H. pylori's ability to induce immune tolerance and limit inflammatory responses. Numerous observational studies have investigated the

Association between hypothyroidism and h
Association between hypothyroidism and hepatocellular carcinoma: A case-control study in the United States
✍ Manal M. Hassan; Ahmed Kaseb; Donghui Li; Yehuda Z. Patt; Jean-Nicolas Vauthey; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 155 KB 👁 1 views

Thyroid hormones play an essential role in lipid mobilization, lipid degradation, and fatty acid oxidation. Hypothyroidism has been associated with nonalcoholic steatohepatitis; however, the association between thyroid diseases and hepatocellular carcinoma (HCC) in men and women has not been well es

Association between obesity and the risk
Association between obesity and the risk of malignant lymphoma in Japanese: a case–control study
✍ Junya Kanda; Keitaro Matsuo; Takeshi Suzuki; Satoyo Hosono; Hidemi Ito; Tatsuo I 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 156 KB 👁 1 views

## Abstract Although marked differences in anthropometric characteristics and malignant lymphoma (ML) incidence suggest that the association between obesity and ML risk in Asian and non‐Asian populations may differ, few studies have investigated this association in Asian populations. Here, we condu

Cutaneous human papillomavirus infection
Cutaneous human papillomavirus infection, the EVER2 gene and incidence of squamous cell carcinoma: A case-control study
✍ Anita S. Patel; Margaret R. Karagas; Michael Pawlita; Tim Waterboer; Heather H. 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 69 KB 👁 1 views

## Abstract The first evidence of an association between HPV and non‐melanoma skin cancer comes from patients with epidermodysplasia verruciformis (EV). EV is a rare heritable disease characterized by cutaneous warts that display not only a high rate of progression to squamous cell carcinoma on sun

The association between 3-hydroxy-3-meth
The association between 3-hydroxy-3-methylglutaryl conenzyme A inhibitor use and breast carcinoma risk among postmenopausal women : A case–control study
✍ Denise M. Boudreau; Jacqueline S. Gardner; Kathleen E. Malone; Susan R. Heckbert 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB 👁 1 views

## Abstract ## BACKGROUND Statin use has increased dramatically in the U.S. in the past decade. Animal and mechanistic studies suggested that statins may have an inhibitory effect on cancer proliferation, including breast carcinoma. However, statins have been found to be carcinogenic in rodents an