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Association between HCV amino acid substitutions and outcome of peginterferon and ribavirin combination therapy in HCV genotype 1b and high viral load

✍ Scribed by Hidenori Toyoda; Takashi Kumada; Toshifumi Tada; Takahiro Arakawa; Kazuhiko Hayashi; Takashi Honda; Yoshiaki Katano; Hidemi Goto

Book ID: 108953667
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 125 KB
Volume: 25
Category: Article
ISSN: 0815-9319
DOI: 10.1111/j.1440-1746.2010.06240.x

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## Abstract A study was carried out to determine whether early viral dynamics retain prediction of the outcome of peginterferon (PEG‐IFN) and ribavirin combination therapy based on different genetic polymorphisms near the __IL28B__ gene, the strongest baseline predictor of response to this therapy.