## Abstract The relative expression of estrogen receptor (ER) and progesterone receptor (PR) mRNA transcripts was measured in 71 primary breastβcancer biopsies. ER and PR binding activity were estimated in parallel by the dextranβcoatedβcharcoal method. There was a close correlation between the amo
Association between breast cancer patient survival and levels of creatine kinase BB in tumor cytosols
β Scribed by N. Zarghami; M. Giai; H. Yu; D. Katsaros; E.P. Diamandis
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 130 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0009-9120
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β¦ Synopsis
CK-BB nctivity is suspected to play a role in the development of breast cancer as CK-BB's transufiptiou enuld be enhanced by estrogen and by oncogene products from adenoviruses. The disruption of CK metabolic pathway could result in a suppression of tumor 8rowth.
Objeet~a To examine if CK-BB aotivity is assnoiated with clinical and pathological feetures of breast canoer and the survival of the patients.
Methoda Tumor tim~ from 172 conseeutlve breast cancer patients were
π SIMILAR VOLUMES
Carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), and the BB isoenzyme of creatine kinase (CK-BB) were evaluated before therapy in the sera of 195 patients with histologically confirmed small cell lung cancer (SCLC) in a prospective multicenter trial. Forty-four percent (84 of 193) of a