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Association and gene–gene interaction of SLC6A4 and ITGB3 in autism

✍ Scribed by D.Q. Ma; R. Rabionet; I. Konidari; J. Jaworski; H.N. Cukier; H.H. Wright; R.K. Abramson; J.R. Gilbert; M.L. Cuccaro; M.A. Pericak-Vance; E.R. Martin


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
106 KB
Volume
153B
Category
Article
ISSN
1552-4841

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The serotonin transporter (5HTT) gene appears to be of particular interest as 5HTT is the selective site of action of selective serotonin reuptake inhibitors (SSRIs) that successfully treat bipolar depression (BP). The 5HTT gene is located on chromosome 17q11.1-q12 and has a 44 bp deletion/insertion