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Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: Increased t allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease

✍ Scribed by Hui Wu; Rita M. Cantor; Deborah S. Cunninghame Graham; Cecilia M. Lingren; Lisa Farwell; Philip L. De Jager; Nunzio Bottini; Jennifer M. Grossman; Daniel J. Wallace; Bevra H. Hahn; Heikki Julkunen; Lee A. Hebert; Brad H. Rovin; Dan J. Birmingham; John D. Rioux; C. Yung Yu; Juha Kere; Timothy J. Vyse; Betty P. Tsao

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 77 KB
Volume: 52
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.21223

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## Abstract ## Objective The R620W (1858C→T) polymorphism in __PTPN2__2 has been implicated in type 1 diabetes mellitus, rheumatoid arthritis, Graves' disease, Hashimoto thyroiditis, autoimmune thyroid disease, and systemic lupus erythematosus (SLE). The aim of this study was to evaluate this poly