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Association analysis of COMT polymorphisms and schizophrenia in a Chinese Han population: A case-control study

โœ Scribed by Rui Yu; Xian-Ning Zhang; Xiao-Xiao Huang; Shi-Ping Ding; Ji-Cheng Li


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
63 KB
Volume
144B
Category
Article
ISSN
1552-4841

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Several linkage studies suggested chromosome 22q11-13 may harbor susceptible genes for schizophrenia. Catechol-0methyl-transferase t:COMT), which is involved in the metabolism of catecholamines, was mapped to 22q'll and is considered a possible candidate gene for schizophrenia. Recently, we identifi