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Assignment of the rat genes coding for α1-antitrypsin (PI), phosphoenolpyruvate carboxykinase (PEPCK), alcohol dehydrogenase (ADH), and fructose-1, 6-bisphosphatase (FDP)

✍ Scribed by Marie-Claude Fulchignoni-Lataud; Josiane Szpirer; Göran Levan; Mary C. Weiss


Book ID
104737685
Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
448 KB
Volume
3
Category
Article
ISSN
0938-8990

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✦ Synopsis


The chromosomal localization of four genes which are expressed mainly in the liver has been undertaken for the rat. Using a panel of hybrid clones segregating rat chromosomes, and Southern blot analysis, od-AT (PI), PEPCK, ADH and FDP are assigned to rat Chromosomes (Chr) 6, 3, 2 and 17, respectively. Groups of synteny among rat, mouse and human species are discussed in relationship to the new assignments.