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Assignment of the gene for glyoxylase I to mouse chromosome 17 by somatic cell genetics

✍ Scribed by Leslie Leinwand; Elizabeth Nichols; Frank H. Ruddle

Publisher
Springer
Year
1978
Tongue
English
Weight
354 KB
Volume
16
Category
Article
ISSN
0006-2928

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✦ Synopsis

Evidence is presented for the assignment of the gene for glyoxylase I to mouse chromosome 17 using mouse x Chinese hamster somatic cell hybrids. GLO I was not expressed concordantly with any known marker enzymes which represented 11 linkage groups. The presence of chromosome 17 and expression of GLO I were concordant in 31/31 clones. GLO I is thus linked to the H-2 histocompatibility locus in the mouse.

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