Seventeen independently derived primary mouse-human hybrid clones were scored for the expression of human phosphoglycolate phosphatase (PGP) by electrophoresis and for the presence of human chromosomes with the aid of Q banding. The correlation of biochemical and cytogenetic analyses shows that the
Assignment of the gene for central core disease to chromosome 19
β Scribed by Eric A. Haan; C. Jane Freemantle; Jill A. McCure; Katherine L. Friend; John C. Mulley
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 307 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0340-6717
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Chimpanzee-mouse hybrid cells were isolated by fusing chimpanzee HGPRT- cells and mouse TK- cells. Both biochemical and cytologic studies of these hybrid cells and BUDR resistant cells isolated from them showed that the TK and GaK genes are located on the chimpanzee chromosome 19.
By means of somatic cell hybrids segregating rat chromosomes, we determined the chromosome localization of three rat genes of the Jun family: Junb (Chr 19), Jun (=c-Jun) (Chr 5) and Jund (Chr 16). The Jun gene was also localized to the 5q31-33 region by fluorescence in situ hybridization. These rat