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Assignment of the amide and aromatic protons of the CHA2-dodecapeptide α-factor from S. Cerevisiae

✍ Scribed by P. Shenbagamurthi; A. S. Steinfeld; S. A. Khan; J. M. Becker; F. Naider


Publisher
Wiley (John Wiley & Sons)
Year
1983
Tongue
English
Weight
301 KB
Volume
22
Category
Article
ISSN
0006-3525

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✦ Synopsis


Cells of the yeast Saccharomyces cerevisiae can exist in two mating types termed aand a-type cells.' Sexual conjugation between a and a cells is mediated by a tridecapeptide pheromone, termed the a-factor, which has a primary structure Trp1His2Trp3Leu4Gln~Leu~Lys7Pro~Gly9Gln1oPro11Met~2Tyr1~. Published structure-activity studies have indicated that the des-Trp' dodecapeptide (His-


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