Assignment of the amide and aromatic protons of the CHA2-dodecapeptide α-factor from S. Cerevisiae
✍ Scribed by P. Shenbagamurthi; A. S. Steinfeld; S. A. Khan; J. M. Becker; F. Naider
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1983
- Tongue
- English
- Weight
- 301 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0006-3525
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✦ Synopsis
Cells of the yeast Saccharomyces cerevisiae can exist in two mating types termed aand a-type cells.' Sexual conjugation between a and a cells is mediated by a tridecapeptide pheromone, termed the a-factor, which has a primary structure Trp1His2Trp3Leu4Gln~Leu~Lys7Pro~Gly9Gln1oPro11Met~2Tyr1~. Published structure-activity studies have indicated that the des-Trp' dodecapeptide (His-
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