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Assignment of Quaternary Carbon Atoms in 13C-NMR Spectroscopy: Application of an improved heteronuclear 2D-NOE experiment

✍ Scribed by Peter Bigler


Publisher
John Wiley and Sons
Year
1988
Tongue
German
Weight
286 KB
Volume
71
Category
Article
ISSN
0018-019X

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✦ Synopsis


Nuclear Overhauser effects (NOE) between protons and heteronuclei can be of great value for the assignment of quaternary nuclei, and they can be very informative and unique in view of stereochemistry and molecular dynamics. The application of a modified 2D-NMR experiment for the assignment of quaternary carbon atoms of a medium-sized molecule is demonstrated. Compared to NMR experiments designed to detect scalar instead of dipolar interactions, measuring times are considerably longer, but data analysis is in many cases more straightforward.