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Assignment of carbonyl groups and sequence analysis in peptides by inverse correlation using long-range couplings

✍ Scribed by Wolfgang Bermel; Christian Griesinger; Horst Kessler; Klaus Wagner

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 194 KB
Volume: 25
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1260250410

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✦ Synopsis

Inverse heteronuclear shift correlation via long-range coupling to the carbonyl carbons of the cyclic hexapeptide cyclo(-Phe1*-Thr'o-AIa9-Trps-Phe7-D-Pro6-) allows the sequential assignment of the amino acids. This experiment has a higher sensitivity than the conventional COLOC sequence.

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