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Assessment of the feasibility of oral controlled release in an exploratory development setting

โœ Scribed by Avinash G. Thombre

Book ID
114385160
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
161 KB
Volume
10
Category
Article
ISSN
1359-6446

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Preclinical assessment of the feasibilit
Preclinical assessment of the feasibility of applying controlled release oral drug delivery to a lead series of atypical antipsychotics
โœ G. Eichenbaum; C. Pollock-Dove; J. Nguyen; S. Li; J. Evans; H. Borghys; L. Kenni ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 248 KB ๐Ÿ‘ 1 views

In this paper, we present a preclinical approach for evaluating the feasibility of applying controlled-release (CR) oral drug delivery to increase the duration of exposure and lower the C max of compounds in a lead series of short half-life atypical antipsychotics. Three lead compounds in the series