Loss of heterozygosity (LOH) and alterations in microsatellite DNA markers have been reported in bladder-cancer tumors. We have studied, in a blinded fashion, using PCRbased microsatellite analysis, genetic alterations of cells exfoliated in urine of 59 Caucasian patients and control patients; 31 wi
β¦ LIBER β¦
Assessment of Microsatellite Instability in Urine in the Detection of Transitional-Cell Carcinoma of the Bladder
β Scribed by Mourah, S.; Cussenot, O.; Vimont, V.; Desgrandchamps, F.; Teillac, P.; Cochant-Priollet, B.; LeDuc, A.; Fiet, J.; Soliman, H.
- Book ID
- 122036606
- Publisher
- Lippincott Williams and Wilkins
- Year
- 1999
- Tongue
- English
- Weight
- 216 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0022-5347
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## Abstract Successful treatment of bladder cancer depends largely on early diagnosis of primary and recurrent disease. Sensitive, specific and noninvasive procedures for detection are especially needed for grade 1 and 2 bladder tumors, because of the relatively low sensitivity of cytology. Here we