## Background: Genetic factors are probably important in the development of gastric carcinoma in young patients (younger than 40 years). the authors investigated early onset primary gastric adenocarcinomas for the presence of microsatellite instability, which is a phenotypic marker for the heredita
Assessment of microsatellite alterations in young patients with gastric adenocarcinoma
✍ Scribed by Raquel Seruca; Manuel Sobrinho-Simões
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 63 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
Marks and Prosnitz were quite right in stating that Survival and LRF in Prognostic Subgroups of Patients with Breast ''final resolution of the controversy regarding the sur-Carcinoma Treated with Mastectomy Alone a vival impact of postmastectomy RT would require a very large prospective trial.'' In such a trial, with the Prognostic 10-year overall 10-year LRF application of modern, ''safe'' RT technique, an unresubgroup No. of patients survival (%) (%) solved issue of the optimal combination of RT and T1 N0 BI b 30 96 7 adjuvant systemic therapy could also be addressed. A T2 N0 BI 80 92 8 question arises as to whether such trial would be feasi-T2 N0 BIII 110 65 23 ble nowadays, when a high proportion of patients are T2 N(1-3) BI 39 73 27 treated with breast-conserving therapy and there is an T2 N(1-3) BII 104 50 29 T2 N¢4 BII 63 41.5 63 increasing interest in neoadjuvant approaches. T2 N¢4 BIII 37 24 70
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