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Assessment of DNA damage in multiple organs of mice after whole body X-irradiation using the comet assay

✍ Scribed by Shunji Ueno; Takashige Kashimoto; Nobuyuki Susa; Hoshiko Natsume; Maiko Toya; Nobuhiko Ito; Shino Takeda-Homma; Yoshikazu Nishimura; Yu F. Sasaki; Masayasu Sugiyama

Book ID
116759333
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
353 KB
Volume
634
Category
Article
ISSN
1383-5718

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DNA damage and cell reproductive death determined by alkaline comet and clonogenic survival assays were examined in Lewis lung carcinoma cells after exposure to 89.63 MeV/u carbon ion and 6 MV X-ray irradiations, respectively. Based on the survival data, Lewis lung carcinoma cells were verified to b