Assessment of differential expression of oncogenes in gastric adenocarcinoma by fluorescent multiplex RT-PCR assay

Numerical aberration and point mutation

Numerical aberration and point mutation of p53 gene in human gastric intestinal metaplasia and well-differentiated adenocarcinoma: Analysis by fluorescence in situ hybridization (FISH) and PCR-SSCP

✍ Yoshihito Gomyo; Mitsuhiko Osaki; Nobuaki Kaibara; Hisao Ito 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 799 KB

This study examined p53 gene alterations in human gastric mucosa, intestinal metaplasia and well-differentiated (cohesive type) adenocarcinomas to clarify to the role of the p53 gene in gastric tumorigenesis by means of fluorescence in situ hybridization (FISH), polymerase-chain-reaction-single-stra