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Assessment of Cocaethylene Lethality in Long–Evans Female and Male Rats

✍ Scribed by B.-F.X. Sobel; A.C. Hutchinson; H.F. Diamond; S.A. Etkind; S.D. Ziervogel; C.M. Ferrari; A.L. Riley

Book ID
114279865
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
53 KB
Volume
20
Category
Article
ISSN
0892-0362

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✍ Judith M. Horowitz; Mark B. Kristal; German Torres 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

Cocaethylene is a neuroactive metabolite derived from the concurrent consumption of cocaine and ethanol. The effects of cocaethylene on locomotor activity, stereotypy, and rearing in Long-Evans and Sprague-Dawley rats were compared. A single cocaine injection (molar equivalent of 60 µmol/kg cocaethy