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Assessment of chromosomal imbalances in CIMP-high and CIMP-low/CIMP-0 colorectal cancers

โœ Scribed by Kozlowska, Joanna; Karpinski, Pawel; Szmida, Elzbieta; Laczmanska, Izabela; Misiak, Blazej; Ramsey, David; Bebenek, Marek; Kielan, Wojciech; Pesz, Karolina A.; Sasiadek, Maria M.


Book ID
118302731
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
184 KB
Volume
33
Category
Article
ISSN
1010-4283

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The loss of genetic material from a specific chromosome region in tumors suggests the presence of tumor-suppressor genes. Loss of heterozygosity (LOH) or allelic imbalance (Al) on the long arm of chromosome 16 is a known event in sporadic breast cancer. To locate the commonly deleted regions, and th