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Assessment of antigenic determinants for the human T cell response against myelin basic protein using overlapping synthetic peptides

โœ Scribed by James Burns; Kimberly Littlefield; Christopher Gomez; Vipin Kumar


Book ID
119107645
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
674 KB
Volume
31
Category
Article
ISSN
0165-5728

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Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a