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Assessing TP53 status in human tumours to evaluate clinical outcome

✍ Scribed by Soussi, Thierry; Béroud, Christophe

Book ID
109776729
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
680 KB
Volume
1
Category
Article
ISSN
1474-1776

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## Abstract The importance of somatic __TP53__ mutations and germline __TP53__ codon 72 genotype in the survival of women with epithelial ovarian cancer is controversial. Recent data suggest that a promoter polymorphism in the __MDM2__ gene may influence age of cancer onset in a gender‐specific fas