Assessing the statistical power to detect linkage in a sample of 51 bipolar affective disorder pedigrees

Genome-wide search for linkage of bipola

Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in Quebec points to a locus of major effect on chromosome 12q23-q24

✍ Morissette, J.; Villeneuve, A.; Bordeleau, L.; Rochette, D.; Laberge, C.; Gagn�, 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB 👁 3 views

We completed a genome-wide scan for susceptibility loci for bipolar affective disorders in families derived from a rather homogeneous population in the Province of Que ´bec. The genetic homogeneity of this population stems from the migration of founding families into this relatively isolated area o